Fantasy Football Week 12 Quarterback And Top 100 Flex Rankings

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Updated: September 4, 2025

  • What to do without the Rams and Chiefs stars
  • Lamar Jackson is a fringe fantasy starter and the highest ranked rookie QB
  • Barkley leads the way in Week 12 with all position leaders on bye

Week 12 sees fantasy owners scrambling to replace Chiefs and Rams stars, as they both are enjoying their bye week, after they put on a epic Monday night performance.

Fantasy managers need backup plans when marquee players are resting. It's not just about losing Mahomes or Gurley for a week, but adjusting lineup depth without them. Smart moves include picking high upside replacements like Justin Jackson or Josh Reynolds.

Beyond selecting individual player substitutes, consider overall strategy refinements during this period. It's a chance to test different team formations or innovate with unconventional plays that might just pay off. For instance, employing a “handcuff” strategy ensures backups for your stars are ready to step in and keep the team steady during their absence.

In leagues with smaller benches, tougher decisions might come into play, making trade negotiations another viable route for temporary adjustments. Looking ahead and planning for these bye weeks can avoid last-minute scrambling and keep your team competitive.

With only the two teams off, lineups won't be as thin as last week. However, the Rams and Chiefs combine for the current leaders in all four offensive positions, with Patrick Mahomes, Todd Gurley, Tyreek Hill, and Travis Kelce all leading their respective position groups.

It's crunch time for fantasy owners so let's get to it.

Read on to find my Top 20 QBs and Top 100 PPR Flex plays heading into Week 12.

If you're looking to mix some fantasy football with more traditional wagers, head over to MyBookie where they have a “Fantasy Betting” option that will allow you to play over/unders on projected fantasy outputs for the week.

Lamar Jackson's Rise as a Rookie QB

Week 12 Top 20 QBs

Rank Player (Team) Opponent Last Weeks Points Points YTD Current 2018 Position Rank DFS Price
1 Drew Brees (NO)  ATL 30.5 239.4 QB 3 $6,700
2 Andrew Luck (IND) MIA 23.9 217 QB 7 $6,400
3 Cam Newton (CAR) SEA 24.5 229.2 QB 5 $6,200
4 Matt Ryan (ATL) @NO 13.7 232.4 QB 4 $6,100
5 Ben Roethlisberger (PIT) @DEN 20.7 227.7 QB 6 $6,100
6 Kirk Cousins (MIN) GB 17 188.4 QB 11 $5,500
7 Carson Wentz (PHI) NYG 0.8 140.6 QB 22 $5,900
8 Tom Brady (NE) @NYJ BYE 175.5 QB 14 $6,500
9 Aaron Rodgers (GB) @MIN 21.6 207.7 QB 9 $5,800
10 Philip Rivers (LAC) ARI 19.6 197.9 QB 10 $5,800
11 Russell Wilson (SEA) @CAR 17.6 187.2 QB 13 $5,600
12 Deshaun Watson (HOU) TEN 9 187.4 QB 12 $6,000
13 Lamar Jackson (BAL) OAK 15.7 43.1 QB 36 $5,700
14 Andy Dalton (CIN) CLE 19.3 166.4 QB 15 $5,300
15 Jameis Winston (TB) SF 15.6 81.9 QB 29 $6,000
16 Baker Mayfield (CLE) @CIN BYE 128.4 QB 26 $5,500
17 Dak Prescott (DAL) WAS 14.8 163.5 QB 17
18 Eli Manning (NYG) @PHI 17.1 153.6 QB 20 $5,700
19 Case Keenum (DEN) PIT 8.2 135.8 QB 25 $4,700
20 Matt Stafford (DET) CHI 13.4 156.7 QB 18

Lamar Jackson's electrifying playstyle has fantasy owners buzzing. His ability to scramble effectively adds a valuable dimension to his game.

In his first start against the Bengals, he netted over 100 rushing yards and secured a win. While still developing as a passer, his rushing potential can significantly impact fantasy scores. Keeping injuries in mind, his use depends on league settings favoring dual-threat QBs.

Keep an eye on Jackson's passing improvement, as his chemistry with receivers grows. This will bolster his fantasy value, especially in leagues where passing touchdowns score highly. Coaches' open-field play designs also boost his output, making him a tempting starter against teams with vulnerable secondary defenses.

Balancing the risk of interceptions with his rushing yard gain is key for capitalizing on his potential each week.

Brees and Ryan Ready for another Heavyweight tilt

Way back in Week 3 the Saints and Falcons combined to put up 80 points. Ryan and Brees were responsible for five a piece. Brees even ran two in, which you can't expect to be repeated.

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But I do expect the offensive outputs to be repeated. The Falcons own one of the league's worst defenses, so whether Ryan is trading blow for blow with Brees, or just playing catch up, it will lead to solid fantasy outputs for both QBs.

Cousins due for a day

Through 10 games the Vikings $84 million investment is looking a little questionable. The Vikings sit at 5-4-1 and a game and a half back of division leader Chicago Bears.

With a huge divisional game on tap for Week 12 against the Aaron Jones-led Packers … Oh, I mean Aaron Rodgers-led Packers, my bad … Cousins could not pick a better spot to prove his worth to his home fans and the front office.

Sure, Cousins hasn't accounted for more than two TDs in a game since Week 4, and has only posted one 300-yard game over his last five outings, but he did put up 425 and 4 TDs in Week 2 against this same Packer defense.

I'd expect that is his ceiling this week, but anywhere close to those numbers makes him worth the investment.

Week 12 Top 100 PPR Flex Rankings

Rank Player (Team)(Pos Rank) Opponent Last Weeks Points Points YTD Current 2018 Position Rank DFS Price
1 Saquon Barkley (NYG)(RB1) @PHI 35.2 252.8 RB 3 $9,100
2 Alvin Kamara (NO)(RB2) ATL 17.8 262.7 RB 2 $8,300
3 Melvin Gordon (LAC)(RB3) ARI 21.6 230.9 RB 5 $8,600
4 Michael Thomas (NO)(WR1) ATL 19.2 230.2 WR 3 $8,900
5 Christian McCaffrey (CAR)(RB4) SEA 17 218.8 RB 7 $7,900
6 Ezekiel Elliot (DAL)(RB5) WAS 33.1 211.4 RB 8
7 James Conner (PIT)(RB6) @DEN 10.9 233.7 RB 4 $7,800
8 Leonard Fournette (JAX)(RB7) @BUF 22.1 63 RB 50 $6,700
9 Odell Beckham Jr (NYG)(WR2) @PHI 18.5 198.4 WR 8 $8,800
10 Davante Adams (GB)(WR3) @MIN 26.6 221.3 WR 4 $8,000
11 Adam Thielen (MIN)(WR4) GB 15.6 230.3 WR 2 $7,800
12 Antonio Brown (PIT)(WR5) @DEN 22.7 208.7 WR 5 $8,700
13 Julio Jones (ATL)(WR6) @NO 23.8 205.8 WR 7 $8,300
14 DeAndre Hopkins (HOU)(WR7) TEN 14.6 206.3 WR 6 $7,900
15 Nick Chubb (CLE)(RB8) @CIN BYE 104.7 RB 27 $6,300
16 David Johnson (ARI)(RB9) @LAC 16.4 169.9 RB 10 $7,300
17 Joe Mixon (CIN)(RB10) CLE 14.2 136.1 RB 17 $6,800
18 Mike Evans (TB)(WR8) SF 24 179.7 WR 11 $7,700
19 TY Hilton (IND)(WR9) MIA 36.5 132.5 WR 23 $6,500
20 Keenan Allen (LAC)(WR10) ARI 24 163.1 WR 15 $7,100
21 Matt Breida (SF)(RB11) @TB BYE 118.6 RB 19 $5,700
22 Phillip Lindsay (DEN)(RB12) PIT 26.6 145.7 RB 12 $5,600
23 Juju Smith-Schuster (PIT)(WR11) @DEN 18.4 171.9 WR 13 $7,500
24 Stefon Diggs (MIN)(WR12) GB 31.6 177.9 WR 12 $7,600
25 AJ Green (CIN)(WR13) CLE INJ 147.7 WR 18 $7,600

PPR leagues bring new strategies to light, where every reception counts towards the score. This format really boosts players like James White and Christian McCaffrey due to their frequent targets.

Slot receivers and pass-catching backs are gold here. Compared to standard leagues, player evaluation shifts as volume of receptions can outscore sheer yardage, shaping drafting and waiver wire decisions differently.

Barkley Keeps The Throne Warm For A Week

Coming off his third 100-yard rushing performance of his rookie season, Barkley is a safe bet at number one overall while Gurley watches at home for a week.

Barkley is averaging over 20 touches per contest for over 120 total yards. His TD per game pace on such a dismal offense is a tribute to his talent.

Eli and the Giants offense have looked more functional the last two weeks following their bye, albeit against the Niners and Bucs, and this week's opponent – division rival Philadelphia Eagles – promises to post a little more resistance.

But Barkley will make his plays. Back in Week 6 he torched the Eagles for 229 total yards and a TD on 22 touches, and will continue to be fed early and often this time around.

Breida Looks Like A Great Daily Play

Flex positions offer a strategic advantage, letting managers slot in an extra RB, WR, or TE. Choosing the right Flex can mean the difference between winning and losing a matchup.

It's all about assessing matchups and potential game scripts. Players like Tarik Cohen, who impact both rushing and receiving, make ideal Flex choices. Rotating this spot based on opponent vulnerabilities keeps lineups fresh.

The Niners own the leagues third-best rushing attack. Yes, the Niners.

Matt Breida is front and center of the production, accumulating 632 yards on only 113 carries. The Niners head into Tampa this week, who own the league's worst scoring defense, giving up 32.9 points a game.

The Bucs are almost middle of the pack against the run, but expect the Niners to try to control the game and keep a scary Bucs offense on the sidelines.

Breida should have a busy week as long as the Niners can keep it close. Breida's daily price of $5,700 saves you a fortune over other top backs and his production has a great chance to match them this week.

Rank Player (Team)(Pos Rank) Opponent Last Weeks Points Points YTD Current 2018 Position Rank DFS Price
26 Zach Ertz (PHI)(TE1) NYG 3.5 187.4 TE 2 $6,400
27 Dalvin Cook (MIN)(RB13) GB 2 44.4 RB 66 $5,400
28 Aaron Jones (GB)(RB14) @MIN 27.3 117.6 RB 20 $6,000
29 James White (NE)(RB15) @NYJ BYE 205.2 RB 9 $7,400
30 Adrian Peterson (WAS)(RB16) @DAL 17.1 141.1 RB 13
31 Tevin Coleman (ATL)(RB17) @NO 11.5 137.1 RB 16 $5,200
32 Marlon Mack (IND)(RB18) MIA 13.9 97.4 RB 33 $5,500
33 Emmanuel Sanders (DEN)(WR14) PIT 10.2 170.7 WR 14 $5,500
34 Josh Gordon (NE)(WR15) @NYJ BYE 94.4 WR 53 $6,400
35 Kenny Golladay (DET)(WR16) CHI 25.3 149.2 WR 17
36 Julian Edelman (NE)(WR17) @NYJ BYE 101.1 WR 49 $7,000
37 George Kittle (SF)(TE2) @TB BYE 147.5 TE 3 $6,200
38 Sony Michel (NE)(RB19) @NYJ BYE 74.4 RB 45 $5,800
39 Lamar Miller (HOU)(RB20) TEN 13.8 105.8 RB 25 $4,500
40 Tarik Cohen (CHI)(RB21) @DET 6 138.9 RB 15
41 Mark Ingram (NO)(RB22) ATL 22.3 89.8 RB 36 $6,100
42 Tyler Boyd (CIN)(WR18) CLE 11.1 161.9 WR 16 $6,000
43 Jarvis Landry (CLE)(WR19) @CIN BYE 131 WR 24 $5,900
44 Alshon Jeffery (PHI)(WR20) NYG 7.3 103.2 WR 44 $5,800
45 Allen Robinson (CHI)(WR21) @DET 6.9 103.7 WR 41
46 Greg Olsen (CAR)(TE3) SEA 8.9 74.7 TE 15 $4,400
47 Chris Carson (SEA)(RB23) @CAR 12.3 88 RB 38 $4,600
48 LeSean McCoy (BUF)(RB24) JAX BYE 93.1 RB 35 $4,200
49 Gus Edwards (BAL)(RB25) OAK 19.5 27.6 RB 74 $4,400
50 Kenyon Drake (MIA)(RB26) @IND BYE 122 RB 18 $4,700

Gus The Bus Enters the Fantasy Discussion

Everyone is on Gus “The Bus” Edwards after a Week 11 performance that saw him running alongside ultra-athletic rookie QB Lamar Jackson and teaming with him for 234 yards.

Edwards was responsible for 115 on 17 carries and a TD.

I'm not fully sold on coach Harbaugh's ringing endorsement, but if Gus is the back to tote the rock for the Ravens while Jackson starts, I want him in my lineup.

Gus Edwards' breakout game has shot him into the fantasy conversation. His style complements Lamar Jackson’s running game, potentially giving him an edge over other Ravens backs.

The combination of Edwards' power running and Jackson's agility could redefine Baltimore's offensive approach. Fantasy managers should monitor his usage closely, as he might become a reliable starter in run-friendly matchups.

Whoever happens to be the primary ball carrier when Jackson is in, I want. Edward's Week 11 performance should have earned the bruising back that chance over the incumbent Alex Collins.

Rank Player (Team)(Pos Rank) Opponent Last Weeks Points Points YTD Current 2018 Position Rank DFS Price
51 Dion Lewis (TEN)(RB27) @HOU 4.2 115.8 RB 21 $4,800
52 Jordan Howard (CHI)(RB28) @DET 7.5 103.3 RB 30
53 Rob Gronkowski (NE)(TE4) @NYJ BYE 77.8 TE 14 $5,100
54  Doug Baldwin (SEA)(WR22) @CAR 18.2 68.7 WR 68 $5,100
55 Amari Cooper (DAL)(WR23) WAS 6.6 93.8 WR 54
56 Calvin Ridley (ATL)(WR24) @NO 6.7 136.9 WR 21 $5,400
57 Tyler Lockett (SEA)(WR25) @CAR 12.2 140.4 WR 20 $5,200
58 Golden Tate (PHI)(WR26) NYG 9 130.8 WR 25 $4,800
59 Larry Fitzgerald (ARI)(WR27) @LAC 16.3 111 WR 33 $5,000
60 DeSean Jackson (TB)(WR28) SF 7.8 142 WR 19 $4,900
61 Keke Coutee (HOU)(WR29) TEN 12.7 59.3 WR 84 $4,600
62 Courtland Sutton (DEN)(WR30) PIT 10.8 80.9  WR 59 $4,400
63 Corey Davis (TEN)(WR31) @HOU 4.9 117.9 WR 28 $5,200
64 Sterling Shepard (NYG)(WR32) @PHI 4.2 124 WR 26 $5,300
65 Peyton Barber (TB)(RB29) SF 19 88.8 RB 37 $3,900
66 Isaiah Crowell (NYJ)(RB30) NE BYE 115.3 RB 22 $4,100
67 Josh Adams (PHI)(RB31) NYG 16.2 33.2 RB 71 $3,800
68 Duke Johnson (CLE)(RB32) @CIN BYE 99.2 RB 31 $5,100
69 Austin Hooper (ATL)(TE5) @NO 6.7 114.5 TE 7 $4,200
70 Trey Burton (CHI)(TE6) @DET 1.9 108.2 TE 8
71 David Njoku (CLE)(TE7) @CIN BYE 84.8 TE 12 $3,800
72 Theo Riddick (DET)(RB33) CHI 8 70.4 RB 47
73 Jalen Richard (OAK)(RB34) @BAL 12.3 106 RB 24 $4,300
74 Austin Ekeler (LAC)(RB35) ARI 8.9 104 RB 29 $3,700
75 Elijah McGuire (NYJ)(RB36) NE BYE 18.4 RB 81 $3,600

The Fantasy World Is A Better Place With Larry Fitzgerald Relevant

After a very unproductive opening six games to the 2018 season, Larry has turned it around and proved there is still production left in his 35-year-old body.


Over the Cardinals last four games, Fitz has caught 20 passes for 215 yards and scored four times on 34 targets.

It's tough relying on bad QBs for fantasy production for your WRs. And make no mistake, rookie Josh Rosen is not currently good, but Fitz has earned his way into the middle of the vast WR3 conversation.

Rank Player (Team)(Pos Rank) Opponent Last Weeks Points Points YTD Current 2018 Position Rank DFS Price
76 Alex Collins (BAL)(RB37) OAK 7.8 108.6 RB 23 $4,500
77 TJ Yeldon (JAX)(RB38) @BUF 5.2 149.5 RB 11 $4,100
78 Nyheim Hines (IND)(RB39) MIA 4.4 104.1 RB 28 $3,600
79 Taylor Gabriel (CHI)(WR33) @DET 13.9 109.1 WR 35
80 Mohamed Sanu (ATL)(WR34) @NO 9.9 103.1 WR 45 $4,500
81 Marquise Goodwin (SF)(WR35) @TB BYE 75.8 WR 63 $5,600
82 Devin Funchess (CAR)(WR36) SEA 5.9 110.6 WR 34 $4,700
83 Danny Amendola (MIA)(WR37) @IND BYE 103.7 WR 41 $4,600
84 Jack Doyle (IND)(TE8) MIA 8.3 48.9 TE 29 $4,100
85 Vance MacDonald (PIT)(TE9) @DEN 11.7 90.7 TE 11 $4,300
86 Cameron Brate (TB)(TE10) SF 3.6 48.9 TE 29 $3,600
87 Jordan Reed (WAS)(TE11) @DAL 20.1 100.2 TE 9
88 Adam Humphries (TB)(WR38) SF 15 108.2 WR 36 $4.000
89 Tyrell Williams (LAC)(WR39) ARI 4.2 111.4 WR 32 $4,700
90 Marquez V-Scantling (GB)(WR40) @MIN 1.8 77 WR 62 $4,800
91 DJ Moore (CAR)(WR41) SEA 28.7 97.6 WR 51 $4,600
92  Chris Godwin (TB)(WR42) SF 8 117.3 WR 29 $4,100
93 Doug Martin (OAK)(RB40) @BAL 6.8 50.2 RB 59 $3,900
94 Mike Davis (SEA)(RB41) @CAR 7 97.6 RB 32 $4,000
95 Derrick Henry (TEN)(RB42) @HOU 4.6 78.1 RB 42 $3,700
96 Royce Freeman (DEN)(RB43) PIT 10 71 RB 46 $3,600
97 Rashaad Penny (SEA)(RB44) @CAR 4.6 52.5 RB 58 $3,700
98 Christian Kirk (ARI)(WR43) @LAC 16.7 104.7 WR 40 $4,500
99 TreQuan Smith (NO)(WR44) ATL 31.7 83.1 WR 58 $4,700
100 Anthony Miller (CHI)(WR45) @DET 10.4 93.2 WR 55

Scanning the Week 12 Bargain Bin

Jack Doyle's return in Week 8 has led to the fading out of first half hero Eric Ebron.

Ebron received no targets in Week 11, and though Doyle only earned four himself, he caught them all for 43 yards.

Since his return, Doyle has hauled in 13 of his 14 targets. With QB Andrew Luck riding hot and spreading the ball around like wildfire, it's hard to rely on any one of the Colts targets. But Doyle's assertion as the starting TE in an offense capable of putting up big points makes him an attractive option at $4,100 in this week's Bargin Bin.

Good luck in Week 12! Happy Turkey Day!

The post Fantasy Football Week 12 Quarterback And Top 100 Flex Rankings appeared first on Sports Betting Dime.

Original source: https://www.sportsbettingdime.com/news/nfl/fantasy-football-week-12-quarterback-and-top-100-flex-rankings/

Andy
Andy
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